Dr Zaid Matti - Musculoskeletal Medicine Specialist
Private Service, Musculoskeletal
Stem Cell Therapy
PURE EXPANDED STEM CELL THERAPY
Every one of us is a collection of over 30 trillion cells. Every one of these cells comes from a single pluripotent type of cell called a stem cell. Stem cells have already changed medicine forever and while they have the ability to extend our lives now they will undoubtedly be saving lives in the near future.
The inherent intelligence of stem cells means they have the ability to differentiate into any other type of cell in the body. While working with ReGen Cellular we are carefully harnessing that intelligence to heal soft tissue such as cartilage, tendons and ligaments, that have been eroded or been depleted through the course of our lives. Science has shown these cells can be woken up by the reintroduction of new healing Mesenchymal Stem Cells. These Mesenchymal Stem Cells release cytokines which are signalling molecules that prime the cells for repair and rejuvenation.
In conjugation with ReGen Cellular, we use proprietary protocols to offer a treatment with the largest concentration of Mesenchymal Stem Cells. Mesenchymal Stem Cells are purified and expanded from patients own fat tissue to hundreds of millions of cells before injection. These Mesenchymal Stem Cells, when mixed with the patient’s own Platelet Rich Plasma, give the body the best chance of repairing damaged cartilage and torn ligaments and tendons and reducing inflammation.
THE EXPANDED STEM CELL PROCESS
We review all medical files, medical history to ascertain suitability and likely success of treatment. Not all patients are suitable candidates for expanded stem cell therapy, and we only treat patients we know have a likely chance of success.
To determine what precisely is causing your pain, we will perform a complete physical examination to understand your lifestyle and what may have triggered the pain. We’ll assess overall biomechanics along with the entire knee to access for pain, swelling, range of motion, stability/laxity, and functional capacity.
Although our physical examination will give us an idea of what’s causing your pain, we’ll often want to confirm our diagnosis with an imaging test. In many cases, this may be a hands-on diagnostic ultrasound to create a live image of your knee to accurately evaluate the soft tissues, tendons, ligaments, and meniscus and to look for joint swelling/bursitis. If a more extensive injury is present involving bone, cartilage or meniscus is suspected, we may promptly obtain MRI.
Harvesting the Stem Cells
Expanded Stem Cell Therapy is based on a solution that is 95% pure Mesenchymal Stem Cells derived from a patient’s own fatty tissue which is a storehouse of these cells. We only offer treatment using a patient’s own adult stem cells. A minor liposuction procedure done under local anaesthetic is carried out to extract 50 grams or two tablespoons of fat. This procedure takes around an hour.
Expanding the Stem Cells
Unlike same-day procedures that only gives a yield of few hundreds of thousands, Expanded Stem Cell is 100-1000 times more than other methods of performing stem cell therapy.
Expanded Stem Cell Therapy is not a same-day procedure. After extraction, growing or multiplying the cells in our laboratory under strict protocols takes up to 8 weeks. The resulting sample is 95% pure Mesenchymal Stem Cells with a yield of between 100 million and 200 million cells.
A mesenchymal stem cell has the ability to:
- Reduce inflammation
- Reduce cell death (Apoptosis)
- Alter the immune response in the arthritic joint and shift it toward healing
Cryo-frozen Stem Cells for Future Use
The expanded stem cells are then carefully cryogenically frozen and stored until your procedure. We produce more stem cells than are needed as this gives our clients the bonus of storing their stem cells for later use.
The additional stem cells can be cryogenically frozen for up to 20 years and used for other damaged joints or tendons in the future. The advantage of this is that no further fat has to be extracted and “younger” stem cells have a greater ability to affect healing later in life. Clients often request further expansions of their cells so they can treat other areas of degeneration.
The Injection Procedure
After informed consent, we take blood from you to create Platelet Rich Plasma. This takes around 15 minutes. Platelets are blood components that are attracted to wound sites where they release cytokines to stimulate the healing and regeneration process. The Platelet Rich Plasma is then mixed with the Mesenchymal Stem Cell serum to protect the cells as well as conditioning them to be more effective at the injury site.
Under precise ultrasound guidance, Platelet Rich Plasma/ Mesenchymal Stem Cell solution is injected. Patients are given a prescription for pain relief but are able to leave immediately.
Follow up and Rehabilitation Program
A follow up with Dr Matti after 2-6 weeks will be organised. Our focus is utilising our treatments and rehabilitation programs towards healing the root cause of your injury or condition without the need for surgery.
We don’t believe in a quick fix, one-size-fits-all approach. Instead, we treat all the structures involved in your condition and enjoy working with our patients to achieve the best outcomes to help them return to normal function and a healthier lifestyle as quickly as possible.